When the owner is also the hirer, the rules change. A lot. Hiring has picked up at firms with fewer than 500 employees. So, you stand a better chance scoring a job in a small pond.
http://management.fortune.cnn.com/2011/04/22/small-companies-are-fertile-ground-for-job-seekers/

But if you only have big-pond experience, here's what you need to know…

The Godin goldens

Seth Godin’s advice on landing a job in a small company hammersthree steps [http://sethgodin.typepad.com/seths_blog/2011/10/how-to-get-a-job-with-a-small-company.html]: 1. Learn to sell.
Everyone has sold something, some time. Small businesses always need people who can sell because selling pays for itself. It’s a profit center. 2. Learn to write.
Writing is a form of selling, one step removed. There’s more writing in business today than ever before. 3. Learn to make extraordinary video and multimedia.
This is just like writing, but for people who don’t like to read. And trymix this skill with significant tech skills.

Your opportunity

Many small businesses don’t take initiative because it feels like risk. And that’s your gap. Take it: work on spec, contribute to a website or a sales letter. Small-business people will say yes – particularly if they’re cash-strapped, profit-oriented and have heard of you.

Your hunt

To find smaller companies, look for:

Your angle

Understand that, in a small company, you’ll:

So, with this mind, tailor your interview andyour resume to the small company gap.